The following information is about Angiogenesis.

Angiogenesis Defined

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Off-site Angiogenesis Links, User Submitted

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Sun Jun 28

• Down Syndrome Yields Key Cancer Clue: People with Down syndrome rarely get solid tumors -- and now researchers are learning why. The answers point to new cancer treatments.

Wed Jun 24

• Unraveling Brain Tumors -- Molecular Biologists Devise Strategy To Starve Brain Tumors

Mon Jun 22

• Role of endothelial progenitors and other bone marrow-derived cells in the development of the tumor vasculature: has a nice summary table of studies - but if they are all as unclear as the Mittal study....
• Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovasculariza tion ? Genes & Development: from the shape - the cells look more like macrophages than mature endothelial cells - very suspicious

Sat Jun 13

• Discovery of new angiogenesis protein - possible cancer drug target
• In vivo properties of the proangiogenic peptide QK

Thu Jun 11

• Gene Therapy Technique Thwarts Cancer By Cutting Off Tumor Blood Supply: ScienceDaily (June 11, 2009) ? University of Florida researchers have come up with a new gene therapy method to disrupt cancer growth by using a synthetic protein to induce blood clotting that cuts off a tumor's blood and nutrient supply. In mice implanted with human colorectal cancer cells, tumor volume decreased 53 percent and cancer cell growth slowed by 49 percent in those treated with a gene that encodes for the artificial protein, compared with those that were untreated.

Wed Jun 10

• UNC scientists identify growth factor as possible cancer drug target: Scientists at the UNC Lineberger Comprehensive Cancer Center report finding a new angiogenesis protein, SFRP2, found in the blood vessels of numerous tumor sites, including breast prostate, lung, pancreas, ovarian, colon, kidney tumors, and angiosarcomas. The scientists found that SFRP2 is a potent stimulator of angiogenesis. This protein may be a favorable target for inhibiting angiogenesis which would then "starve&q uot; the tumor of its blood supply, thus destroying the cancer.

Mon Jun 8

• Biomechanical regulation of blood vessel growth during tissue vascularizatio n : Article : Nature Medicine: an additional method for initial angiogenesis - pulling the existing vessels into the healing wound! Maybe more relevant for normal wound healing than tumors - or not?

Thu May 28

• Angiogenesis - National Cancer Institute

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Off-site Angiogenesis Research Links

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